To systematically review clinical practice guidelines (CPGs) on diabetes foot and assess the consistency of recommendations, quality of CPGs and to present an evidence-map for explicating research trends and gaps. We performed a literature search on PubMed, Embase, and Web of Science, guideline databases and websites of diabetes society to include the diabetic CPGs. The basic information, recommendations for the diabetic foot, methodological quality and reporting quality of diabetic CPGs were exacted by the Excel. Four researchers evaluated the methodological and reporting quality of diabetic foot CPGs by AGREE II instrument and RIGHT checklist. R3.5.1 software was used to create all bubble plots. A total of 22 diabetic CPGs were included, eight CPGs were from different professional diabetes societies. Recommendations on diabetic foot complications involve Diabetic foot ulcer (DFU), Charcot neuropathy (CN) and Osteomyelitis (OM). Eight DFU diagnostic systems presented in 22 CPGs. According to the recommendations of diabetic CPGs, the treatment of DFU can be summarized in four major items; six recommendations on CN diagnosis and six recommendations on treatment of CN were consistent among studies. However, there were inconsistencies in three OM diagnosis recommendations and four OM treatment recommendations. Some recommendations in CPGs were not very specific and clear, and hence they were not reliable for OM diagnosis and treatment. Once these inconsistencies are resolved, validated, accurate and effective diagnosis and treatment of diabetes foot will lead to reduced costs and adverse complications. The results of this review add to our knowledge and promote the development of trustworthy CPGs on diabetes.

中文翻译：

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关于糖尿病足的诊断和治疗策略的建议的证据图谱：22条指南的国际回顾。

要系统地审查关于糖尿病足的临床实践指南（CPG），并评估建议的一致性，CPG的质量，并提出证据图以阐明研究趋势和差距。我们在PubMed，Embase和Web of Science，指南数据库和糖尿病学会网站上进行了文献检索，以纳入糖尿病CPG。Excel准确记录了糖尿病足CPG的基本信息，有关糖尿病足的建议，方法学质量和报告质量。四名研究人员通过AGREE II仪器和RIGHT检查表评估了糖尿病足CPG的方法学和报告质量。使用R3.5.1软件创建所有气泡图。总共包括22种糖尿病CPG，其中8种CPG来自不同的专业糖尿病学会。关于糖尿病足并发症的建议包括糖尿病足溃疡（DFU），夏科神经病（CN）和骨髓炎（OM）。在22个CPG中提供了八个DFU诊断系统。根据糖尿病CPG的建议，DFU的治疗可归纳为四个主要项目。研究中关于CN诊断的6条建议和关于CN治疗的6条建议是一致的。但是，三项OM诊断建议和四项OM治疗建议不一致。CPG中的某些建议不是很明确和明确，因此对于OM诊断和治疗不可靠。一旦这些矛盾得到解决，验证，准确和有效的糖尿病足诊断和治疗，将导致成本降低和不良并发症。