PURPOSE To analyze and compare the surface properties of commercially available hydrophobic acrylic intraocular lenses (IOLs). SETTING Eye Clinic, University of Trieste, Italy. DESIGN Experimental study. METHODS The following 6 single-piece hydrophobic acrylic IOL models with the same dioptric power were studied and compared: Clareon SY60WF, Tecnis PCB00, enVista MX60, CT Lucia 601P, Vivinex iSert XY1, and iSert 251. Topography of the IOL surface was analyzed using atomic force microscopy (AFM). Surface contact angle measurements using the sessile drop method were performed to assess IOL wettability. RESULTS The AFM analysis showed that the Vivinex iSert XY1 IOL and Clareon SY60WF IOL had the lowest surface roughness (P < .05); there was no statistically significant difference in surface roughness between the those 2 IOL models (P > .05). Surface contact angle measurements showed that the iSert 251 IOL had the highest hydrophobicity. The CT Lucia 601P IOL had the lowest contact angle of all IOL models. CONCLUSIONS The AFM analysis and surface contact angle measurements of all IOLs tested showed that the Vivinex iSert XY1 IOL and Clareon SY60WF IOL had the best topographic features. The smoother, more regular surface of these new IOL models might reduce cell adhesion and therefore lower the incidence of posterior capsule opacification.

中文翻译：

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市售疏水性丙烯酸人工晶状体的表面性质：比较研究。

目的分析和比较市售疏水性丙烯酸人工晶状体（IOL）的表面性能。设置眼科诊所，意大利的里雅斯特大学。设计实验研究。方法研究并比较了以下6种具有相同屈光度的单片疏水丙烯酸IOL模型：Clareon SY60WF，Tecnis PCB00，enVista MX60，CT Lucia 601P，Vivinex iSert XY1和iSert 251。原子力显微镜（AFM）。使用无滴法进行表面接触角测量，以评估IOL的可湿性。结果AFM分析表明，Vivinex iSert XY1 IOL和Clareon SY60WF IOL具有最低的表面粗糙度（P <.05）；在这两个IOL模型之间，表面粗糙度在统计学上没有显着差异（P> .05）。表面接触角测量表明，iSert 251 IOL具有最高的疏水性。CT Lucia 601P IOL具有所有IOL型号中最低的接触角。结论所有测试的IOL的AFM分析和表面接触角测量表明，Vivinex iSert XY1 IOL和Clareon SY60WF IOL具有最佳的形貌特征。这些新的IOL模型的表面更光滑，更规则的表面可能会减少细胞粘附，从而降低后囊混浊的发生率。