Journal of Hospital Infection ( IF 3.9 ) Pub Date : 2019-07-27 , DOI: 10.1016/j.jhin.2019.07.013 R. Stauf , D. Todt , E. Steinmann , P-M. Rath , H. Gabriel , J. Steinmann , F.H.H. Brill
The biocidal activities of peracetic acid and ethanol were tested against nine clinical fungal isolates and four reference strains. Ethanol was active (≥4.0 log10 reduction) against yeasts at a concentration of 50% v/v and against moulds at 80% v/v. Exposure times in both cases were 1 min. Peracetic acid was active as a 0.25% solution against yeasts and as a 0.5% solution against moulds; exposure times in both cases were 5 min. Compared with the reference strains, clinical isolates, including multi-drug-resistant strains, showed similar or higher sensitivity to the active ingredients of disinfectants in vitro.
中文翻译:
消毒剂有效成分对耐药真菌的体外活性
测试了过氧乙酸和乙醇的杀菌活性,针对九种临床真菌分离物和四种参考菌株。乙醇对酵母(浓度为50%v / v)和霉菌(对霉菌的浓度为80%v / v)具有活性(降低了4.0 log 10)。两种情况下的曝光时间均为1分钟。过乙酸的活性为0.25%的溶液对酵母和0.5%的溶液对霉菌;两种情况下的暴露时间均为5分钟。与参考菌株相比,包括多药耐药菌株在内的临床分离株对体外消毒剂的活性成分表现出相似或更高的敏感性。