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Molecular epidemiology of an outbreak of human parainfluenza virus 3 among oncology patients.
Journal of Hospital Infection ( IF 3.9 ) Pub Date : 2019-07-26 , DOI: 10.1016/j.jhin.2019.07.012
E S Bailey 1 , E Lobaugh-Jin 2 , B Smith 3 , C Sova 2 , J Misuraca 4 , N Henshaw 5 , G C Gray 6
Affiliation  

A hospital outbreak of human parainfluenza virus type 3 (HPIV-3) in haematologic oncology patients is described in 12 patients over a four-week period. Exposure histories and molecular analysis of HPIV-3 isolates suggest that both community-acquired and nosocomially transmitted infections occurred during this outbreak. Molecular analysis of HPIV-3 isolates indicated that a chain of transmission occurred among multiple patients in an oncology ward. This transmission was later determined to be associated with the movement of fomites, visitors, and activities in the unit. The infection prevention team stopped nosocomial spread of HPIV-3 through interventions including advanced cleaning procedures.

中文翻译:

肿瘤患者中人副流感病毒3爆发的分子流行病学。

在四周的时间内,有12名患者描述了在血液系统肿瘤患者中发生的3型人副流感病毒(HPIV-3)医院暴发。HPIV-3分离株的接触史和分子分析表明,在此暴发期间既发生了社区获得性感染,也发生了医院内传播的感染。HPIV-3分离物的分子分析表明,在肿瘤病房中,多名患者之间发生了传播链。后来确定此传播与该单元中的炸弹袭击者,来访者和活动有关。感染预防小组通过包括先进清洁程序在内的干预措施,阻止了HPIV-3在医院的传播。
更新日期:2019-11-18
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