This study investigated the effects of fermented soybean meal (FSBM) with or without mannan-oligosaccharide (MOS) prebiotic on growth performance, digestive functions, and hepatic IGF-1 gene expression of broiler chicken. A total of 480 day-old male broiler chickens were fed with 4 experimental diets for 6 wk. Experimental diets included corn-soybean meal diet (CON); corn-soybean meal diet + MOS prebiotic [0.2%, ActiveMOS; Biorigin, Brazile]; corn-FSBM diet [soybean meal (SBM) was totally replaced by FSBM]; and corn-FSBM + MOS prebiotic (MIX). Replacing dietary SBM with FSBM with or without MOS improved body weight gain and feed efficiency for the total grow-out period. However, the addition of MOS to the FSBM diet exhibited a greater body weight gain than other experimental diets. Villus height and villus height to crypt depth of the duodenum and jejunum were increased by feeding FSBM, MOS, and MIX diets. The ileal crude protein and energy digestibilities, as well as the activities of intestinal amylase and protease, and pancreatic protease, were improved by replacing SBM with FSBM, with or without MOS. The concentration of plasma 3-methylhistidine was reduced by FSBM and MOS, and synergistically by their combination. The MOS and FSBM diets upregulated the hepatic IGF-1 gene expression. However, there was an evident synergistic effect of FSBM supplemented with MOS in the upregulation of the hepatic IGF-1 gene expression. The outcomes of the current study indicate the FSBM and MOS had the potential to improve growth performance, hepatic IGF-1 expression, and intestinal morphology of broilers. Overall, the fermented products could be considered as functional feed that exhibits probiotic effects and the synergistic effects of prebiotics added to the fermented feeds may further improve the growth performance and gut health and functionality in broiler chicken.

中文翻译：

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发酵豆粕和甘露寡糖对肉鸡生长性能、消化功能和肝脏基因表达的协同作用。


本研究调查了含有或不含甘露寡糖 (MOS) 益生元的发酵豆粕 (FSBM) 对肉鸡生长性能、消化功能和肝脏 IGF-1 基因表达的影响。总共 480 日龄的雄性肉鸡用 4 种实验饲料喂养 6 周。实验饮食包括玉米-豆粕饮食（CON）；玉米豆粕饮食+MOS益生元[0.2%，ActiveMOS； Biorigin，巴西]；玉米-FSBM饮食[豆粕(SBM)完全被FSBM取代]；和玉米-FSBM + MOS 益生元 (MIX)。用含有或不含有 MOS 的 FSBM 代替日粮 SBM 可以改善整个生长阶段的体重增加和饲料效率。然而，在 FSBM 饮食中添加 MOS 比其他实验饮食显示出更大的体重增加。通过饲喂 FSBM、MOS 和 MIX 日粮，绒毛高度以及十二指肠和空肠的绒毛高度至隐窝深度均增加。通过用 FSBM 替代 SBM（无论有或没有 MOS），回肠粗蛋白和能量消化率以及肠淀粉酶和蛋白酶以及胰腺蛋白酶的活性均得到改善。 FSBM 和 MOS 可以降低血浆 3-甲基组氨酸的浓度，并且它们的组合可以协同降低血浆 3-甲基组氨酸的浓度。 MOS 和 FSBM 饮食上调肝脏 IGF-1 基因表达。然而，FSBM补充MOS在上调肝脏IGF-1基因表达方面具有明显的协同作用。目前的研究结果表明，FSBM 和 MOS 具有改善肉鸡生长性能、肝脏 IGF-1 表达和肠道形态的潜力。 总的来说，发酵产品可以被认为是具有益生菌作用的功能性饲料，并且添加到发酵饲料中的益生元的协同作用可以进一步改善肉鸡的生长性能以及肠道健康和功能。