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Keeping the Death Protein in Check
Immunity ( IF 25.5 ) Pub Date : 2019-07-16 , DOI: 10.1016/j.immuni.2019.06.011 Longfei Wang 1 , Hao Wu 1
中文翻译:
控制死亡蛋白
更新日期:2019-07-17
Immunity ( IF 25.5 ) Pub Date : 2019-07-16 , DOI: 10.1016/j.immuni.2019.06.011 Longfei Wang 1 , Hao Wu 1
Affiliation
Gasdermin D is an executioner of inflammatory cell death. In this issue, Liu et al. report the crystal structures of full-length human and mouse gasdermin D, which contributes to our understanding of gasdermin D autoinhibition and activation and will inform the future development of therapeutics targeting gasdermin D.
中文翻译:
控制死亡蛋白
Gasdermin D 是炎症细胞死亡的执行者。在这个问题上,刘等人。报告了全长人和小鼠 gasdermin D 的晶体结构,这有助于我们了解 gasdermin D 的自抑制和激活,并将为针对 gasdermin D 的疗法的未来发展提供信息。