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Consumer exposure and risk assessment to selected chemicals of mold stain remover use in Korea.
Journal of Exposure Science and Environmental Epidemiology ( IF 4.5 ) Pub Date : 2019-07-12 , DOI: 10.1038/s41370-019-0155-0
Ji Young Park 1 , Miyoung Lim 2 , Kiyoung Lee 1, 2 , Kyunghee Ji 3 , Wonho Yang 4 , Ho-Sang Shin 5 , Hyunhee Lim 5 , Hunjoo Lee 6 , Jaehoon An 7
Affiliation  

Mold stain remover (MSR) is used to clean mold and mildew spots from surfaces and contains a variety of chemical substances. In this study, we estimated the inhalation and dermal exposures associated with the use of trigger spray MSRs, and performed screening-level risk assessments for the use of this type of product in Korea. Inhalation and dermal exposures were estimated using exposure algorithms based on exposure factors obtained from a nationwide survey of 10,000 participants and chemical analyses of the four most popular trigger spray MSRs. The hazard quotients (HQs) for noncancer risk and excess cancer risk (ECR) were calculated for each chemical. The mean inhalation exposure estimates for formaldehyde, benzene, chloroform, and carbon tetrachloride were 6.9 × 10−7, 1.7 × 10−7, 5.4 × 10−6, and 2.7 × 10−5 mg/kg/day, respectively. Dermal exposures of the chemicals were 5.7–6.5 times higher than inhalation exposures. The HQs for total exposure were all below 1, which indicated little noncancer risk from the use of MSRs. The safe ECR value of 1 × 10−6, was exceed in one subject for inhalation exposure of benzene and four subjects for dermal exposure of formaldehyde, while 19.8% for dermal exposure of benzene were above this value. Therefore, use of trigger spray MSRs in Korea should require more detailed exposure and risk assessment, especially for benzene.



中文翻译:

在韩国,消费者对使用脱模剂的某些化学品的接触和风险评估。

霉菌去除剂(MSR)用于清洁表面的霉菌和霉斑,并包含多种化学物质。在这项研究中,我们估算了与使用触发喷雾剂MSR相关的吸入和皮肤接触,并在韩国对该类产品的使用进行了筛查级风险评估。吸入和皮肤接触是根据暴露算法估算的,该算法基于对10,000名参与者进行的全国性调查以及对四种最受欢迎​​的触发喷雾MSR的化学分析得出的接触因子。计算每种化学品的非癌症风险和过度癌症风险(ECR)的危险商(HQs)。甲醛,苯,氯仿和四氯化碳的平均吸入接触估计为6.9×10 -7,1.7 ×10 -7,分别为5.4×10 -6和2.7×10 -5  mg / kg /天。化学品的皮肤暴露量比吸入暴露量高5.7-6.5倍。总暴露的HQ均低于1,表明使用MSR的非癌风险很小。一名吸入苯的受试者和4名受试者经甲醛的皮肤暴露均超过了1×10 -6的安全ECR值,而经苯皮肤的甲醛暴露则超出了19.8%的安全ECR值。因此,在韩国使用扳机式喷雾MSR应该需要更详细的暴露和风险评估,尤其是对于苯。

更新日期:2019-11-18
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