Pancreatic neuroendocrine tumours (PanNET) are rare tumours, accounting for 1%-2% of all pancreatic neoplasms. These tumors are classified as functioning neuroendocrine tumours (F-PanNETs) or non-functioning (NF-PanNETs) depends on whether the tumour is associated with clinical hormonal hypersecretion syndrome or not. In the last decades, diagnosis of PanNETs has increased significantly due to the widespread of cross-sectional imaging. Whenever possible, surgery is the cornerstone of PanNETs management and the only curative option for these patients. Indeed, after R0 resection, the 5-year overall survival rate is around 90-100% for low grade lesions but significantly drops after incomplete resections. Compared to standard resections, pancreatic sparing surgery, i.e. enucleation and central pancreatectomy, significantly decreased the risk of pancreatic insufficiency. It should be performed in patients with good general condition and normal pancreatic function to limit the operative risk and enhance the benefit of surgery. Nowadays, due to many known advantages of minimally invasive surgery, there is an ongoing trend towards laparoscopic and robotic pancreatic surgery. The aim of this study is to describe the pre- and intraoperative diagnostic requirements for the management of PanNETs and the benefits and risks of minimally invasive surgery including laparoscopic and robotic approach in view of the recent literature.

中文翻译：

---

微创和机器人手术对胰腺神经内分泌肿瘤的术前和术中诊断要求，收益和风险。

胰腺神经内分泌肿瘤（PanNET）是罕见的肿瘤，占所有胰腺肿瘤的1％-2％。这些肿瘤被分类为功能性神经内分泌肿瘤（F-PanNETs）或无功能性（NF-PanNETs），取决于该肿瘤是否与临床荷尔蒙分泌过多综合征相关。在过去的几十年中，由于横截面成像的广泛应用，对PanNET的诊断已大大增加。只要有可能，手术都是PanNETs管理的基石，也是这些患者的唯一治疗选择。确实，在R0切除后，低度病变的5年总生存率约为90-100％，但在不完全切除后显着下降。与标准切除相比，保留胰腺手术（即摘除术和中央胰腺切除术）显着降低了胰腺功能不全的风险。一般情况良好且胰腺功能正常的患者应进行手术，以限制手术风险并提高手术获益。如今，由于微创手术的许多已知优势，腹腔镜和机器人胰腺手术的趋势不断发展。这项研究的目的是根据最近的文献描述PanNETs的术前和术中诊断要求以及包括腹腔镜和机器人方法在内的微创手术的收益和风险。由于微创外科手术的许多已知优点，因此，腹腔镜和机器人胰腺手术的趋势不断发展。这项研究的目的是根据最近的文献描述PanNETs的术前和术中诊断要求以及包括腹腔镜和机器人方法在内的微创手术的收益和风险。由于微创外科手术的许多已知优点，因此，腹腔镜和机器人胰腺手术的趋势不断发展。这项研究的目的是根据最近的文献描述PanNETs的术前和术中诊断要求以及包括腹腔镜和机器人方法在内的微创手术的收益和风险。