Study design A cross-sectional multi-center study using an on-line survey addressing utilization, knowledge, and perceptions of medicinal cannabis (MC) by people with spinal cord injury (SCI). Objective To characterize differences between current (CU), past (PU), and never users (NU) of MC with SCI; to determine why people with SCI use MC; to examine reports of MCs' efficacy and tolerability by individuals with SCI. Setting Three academic medical centers in the United States. Methods Comparison of demographic and attitudinal differences between CU, PU, and NU and differences in the groups' reports of pain, health, and quality of life (QOL). Evaluation of utilization patterns and perceived efficacy of MC among CU and PU and reports of side effects of MC versus prescription medications. Data were analyzed using either Chi Square, distribution-free exact statistics, or t-tests for continuous data. Results Among a nationwide sample (n = 353) of individuals with SCI, NU were less likely than CU and PU to believe that cannabis ought to be legalized and more likely to endorse risks of use. Current users and PU reported greater pain interference in daily life than did NU, but there were no between group differences in QOL or physical or emotional health. Current users and PU took MC to address pain (65.30%), spasms (63.30%), sleeplessness (32.70%), and anxiety (24.00%), and 63.30% reported it offered "great relief" from symptoms. Participants reported that MC is more effective and carries fewer side effects than prescription medications. Conclusions Medicinal cannabis is an effective and well-tolerated treatment for a number of SCI-related symptoms.

中文翻译：

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脊髓损伤患者利用药用大麻缓解疼痛。


研究设计一项横断面多中心研究，使用在线调查来解决脊髓损伤（SCI）患者对药用大麻（MC）的利用、知识和看法。目的 描述当前 (CU)、过去 (PU) 和从未使用 MC 的用户 (NU) 与 SCI 之间的差异；确定 SCI 患者使用 MC 的原因；检查 SCI 患者的 MC 功效和耐受性报告。在美国设立三个学术医疗中心。方法 比较 CU、PU 和 NU 之间的人口统计学和态度差异以及各组疼痛、健康和生活质量 (QOL) 报告的差异。评估 CU 和 PU 中 MC 的使用模式和感知功效，以及 MC 与处方药相比副作用的报告。使用卡方、无分布精确统计或连续数据的 t 检验来分析数据。结果 在全国范围内的 SCI 个体样本（n = 353）中，NU 比 CU 和 PU 更不可能相信大麻应该合法化，并且更有可能认可使用大麻的风险。当前用户和 PU 报告日常生活中的疼痛干扰比 NU 更大，但组间在生活质量或身体或情绪健康方面没有差异。目前的使用者和 PU 服用 MC 来缓解疼痛（65.30%）、痉挛（63.30%）、失眠（32.70%）和焦虑（24.00%），63.30% 的人表示它可以“极大地缓解”症状。参与者报告说，MC 比处方药更有效且副作用更少。结论 药用大麻是治疗多种 SCI 相关症状的有效且耐受性良好的方法。