Disorders of sex development (DSD) are a group of complex conditions that can affect chromosomal, gonadal, and/or phenotypical sex with a highly variable fertility potential amongst affected individuals. In this review we discuss fertility issues facing patients affected by DSD and Turner syndrome and summarise the literature on fertility and reproductive outcomes. We will also discuss fertility preservation prior to gonadotoxic treatment in adolescent and prepubertal girls. Future directions in fertility preservation and ethical issues will also be addressed. Fertility preserving options that are established include ovarian tissue and oocyte cryopreservation. However, in many of the DSDs fertility is not possible and the discussion may need to move toward alternative methods of creating a family such as gamete donation or surrogacy.

中文翻译：

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在DSD中保留女性生育力。

性发育障碍（DSD）是一类复杂的疾病，可以影响染色体，性腺和/或表型性行为，受累个体之间的生育能力差异很大。在这篇综述中，我们讨论了受DSD和Turner综合征影响的患者面临的生育问题，并总结了有关生育和生殖结局的文献。我们还将讨论青春期和青春期前女孩在性腺毒性治疗之前的生育力保存。在生育保护和道德问题方面的未来方向也将得到解决。确定的生育能力选择包括卵巢组织和卵母细胞冷冻保存。但是，在许多DSD中，生育是不可能的，因此讨论可能需要转向建立家庭的替代方法，例如配子捐赠或代孕。