The structural and functional properties of neurons have intrigued scientists since the pioneering work of Santiago Ramón y Cajal. Since then, emerging cutting-edge technologies, including light and electron microscopy, electrophysiology, biochemistry, optogenetics, and molecular biology, have dramatically increased our understanding of dendritic properties. This advancement was also facilitated by the establishment of different animal model organisms, from flies to mammals. Here we describe the emerging model system of a Caenorhabditis elegans polymodal neuron named PVD, whose dendritic tree follows a stereotypical structure characterized by repeating candelabra-like structural units. In the past decade, progress has been made in understanding PVD's functions, morphogenesis, regeneration, and aging, yet many questions still remain.

中文翻译：

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蠕虫树突图案的经验教训。

自圣地亚哥·拉蒙·卡哈尔（SantiagoRamóny Cajal）的开创性工作以来，神经元的结构和功能特性吸引了科学家的兴趣。从那时起，新兴的尖端技术，包括光电子显微镜，电生理学，生物化学，光遗传学和分子生物学，极大地增加了我们对树突性质的理解。从果蝇到哺乳动物的不同动物模型生物的建立也促进了这一进步。在这里，我们描述了秀丽隐杆线虫多峰神经元称为PVD的新兴模型系统，其树突状树遵循以重复大烛台状结构单元为特征的定型结构。在过去的十年中，在理解PVD的功能，形态发生，再生和衰老方面取得了进展，但是仍然存在许多问题。