The second article in this continuing medical education series reviews the initial evaluation of patients with suspected dermatomyositis (DM), the relevant work-up for malignancy and interstitial lung disease once a diagnosis of DM is made, and treatment recommendations for patients with DM based on disease severity, the presence of systemic symptoms, and myositis-specific antibody (MSA) profiles. This review emphasizes the emerging role of MSAs in the diagnosis of DM and highlights how MSAs can be used to guide the appropriate work-up for malignancy and interstitial lung disease. The treatment approach proposed by this continuing medical education series discusses both established and novel therapies for DM and highlights the importance of considering lesion type, degree of muscle involvement, presence of systemic symptoms, presence of MSAs, and patient age when determining the best treatment approach for a patient with DM.

中文翻译：

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皮肌炎：诊断和治疗。

该继续医学教育系列的第二篇文章回顾了对可疑皮肌炎（DM）患者的初步评估，对DM诊断后对恶性肿瘤和间质性肺疾病的相关检查，以及针对基于DM的DM患者的治疗建议疾病严重程度，全身症状的存在以及肌炎特异性抗体（MSA）资料。这篇综述强调了MSA在DM诊断中的新兴作用，并强调了如何使用MSA指导对恶性和间质性肺疾病进行适当的检查。这个持续医学教育系列提出的治疗方法讨论了DM的既有疗法和新型疗法，并强调了考虑病变类型，肌肉受累程度，全身症状的存在，MSA的存在，