BACKGROUND AND AIMS A novel device that provides real-time depiction of functional luminal image probe (FLIP) panometry (ie, esophagogastric junction [EGJ] distensibility and distension-induced contractility) was evaluated. We aimed to compare real-time FLIP panometry interpretation at the time of sedated endoscopy with high-resolution manometry (HRM) in evaluating esophageal motility. METHODS Forty consecutive patients (aged 24-81 years; 60% women) referred for endoscopy with a plan for future HRM from 2 centers were prospectively evaluated with real-time FLIP panometry during sedated upper endoscopy. The EGJ distensibility index and contractility profile were applied to derive a FLIP panometry classification at the time of endoscopy and again (post-hoc) using a customized program. HRM was classified according to the Chicago classification. RESULTS Real-time FLIP panometry motility classification was abnormal in 29 patients (73%), 19 (66%) of whom had a subsequent major motility disorder on HRM. All 9 patients with an HRM diagnosis of achalasia had abnormal real-time FLIP panometry classifications. Eleven patients (33%) had normal motility on real-time FLIP panometry and 8 (73%) had a subsequent HRM without a major motility disorder. There was excellent agreement (κ = .939) between real-time and post-hoc FLIP panometry interpretation of abnormal motility. CONCLUSIONS This prospective, multicentered study demonstrated that real-time FLIP panometry could detect abnormal esophageal motility, including achalasia, at the endoscopic encounter. Additionally, normal motility on FLIP panometry was predictive of a benign HRM. Thus, real-time FLIP panometry incorporated with endoscopy appears to provide a suitable and well-tolerated point-of-care esophageal motility assessment.

中文翻译：

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内窥镜检查时可以建立食管动力分类：一项评估实时功能性腔成像探头全景测量的研究。

背景和目的评估了一种新颖的设备，该设备提供功能性腔内图像探针（FLIP）全景测量（即食管胃交界处[EGJ]可扩张性和扩张性收缩力）的实时描绘。我们旨在比较镇静内窥镜检查时实时FLIP全景图解释与高分辨率测压法（HRM）在评估食道运动性方面的优势。方法在镇静性上镜内窥镜检查期间，采用实时FLIP全景测量法对40个连续患者（年龄在24-81岁； 60％的女性）进行了内窥镜检查，并计划从两个中心进行未来HRM的评估。在内窥镜检查时使用EGJ的可膨胀指数和收缩曲线来导出FLIP全景图分类，然后使用定制程序再次（事后）。人力资源管理根据芝加哥分类进行分类。结果29例患者（73％）的实时FLIP眼动仪运动分类异常，其中19人（66％）随后发生了HRM的主要运动障碍。所有9例HRM诊断为门失弛缓症的患者，其实时FLIP全景图分类均异常。实时FLIP眼压计的11例患者（33％）的运动能力正常，其后的HRM患者中有8例（73％）没有严重的运动能力障碍。实时和事后FLIP全景图对异常运动的解释之间存在极好的一致性（κ= .939）。结论这项前瞻性，多中心研究表明，实时FLIP压力计可以在内窥镜检查中检测到异常的食道运动，包括门失弛缓。此外，FLIP压力计的正常运动可预示良性HRM。因此，