Holding-Oriented versus Gating-Oriented Live-Cell Distinction: Highlighting the Role of Transporters in Cell Imaging Probe Development.,Accounts of Chemical Research

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Holding-Oriented versus Gating-Oriented Live-Cell Distinction: Highlighting the Role of Transporters in Cell Imaging Probe Development.
Accounts of Chemical Research ( IF 16.4 ) Pub Date : 2019-07-02 , DOI: 10.1021/acs.accounts.9b00253
Yun-Kyu Choi ₁ , Jong-Jin Kim ₂ , Young-Tae Chang _{1,

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Affiliation

Small molecule imaging probes are powerful tools to understand complex biological systems. The mainstreams of imaging probe developments have been focused on the target holding of the probes; the holding targets are often cell-type-specific biomarkers. This type of the probe mechanism can be designated as holding-oriented live-cell distinction (HOLD).

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