Gastric cancer is the fifth commonest cancer and remains the world’s third leading cause of cancer mortality.¹ Surgery is the mainstay of curative treatment in stage I to III gastric cancers. However, more than half of the patients at diagnosis are already too advanced for curative resection. Even for those who are resectable upfront, the recurrence rate is still high at around 40–80%.^2,3

中文翻译：

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晚期/转移性胃癌的三线全身治疗：综述

胃癌是第五种最常见的癌症，仍然是世界第三大导致癌症死亡的主要原因。¹外科手术是治疗I至III期胃癌的主要手段。但是，诊断时超过一半的患者已经晚期而无法进行根治性切除。即使对于那些可预先切除的患者，复发率仍然很高，约为40-80％。^2,3