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Is there an association between prenatal oral healthcare and early childhood caries prevention?
Evidence-Based Dentistry Pub Date : 2019-06-01 , DOI: 10.1038/s41432-019-0027-4
Niall McGoldrick 1 , Jacky Burns 1 , Morag Muir 2
Affiliation  

Data sources Database searches included Pubmed, Embase, Scopus, Web of Science, LILACS, Cochrane Library and ClinicalTrials.gov.Study selection This review included studies that assessed the impact of pre-natal oral health care on early childhood caries experience and/or oral carriage of S. mutans. The review included case control studies, retrospective or prospective cohort studies, randomised or non-randomised controlled trials. In vitro studies, animal studies, literature reviews, cross sectional studies and literature reviews were excluded.Data extraction and synthesis Two calibrated and independent reviewers screened the literature using a data extraction form based on defined inclusion and exclusion criteria. A PRISMA flow diagram is presented showing the process of reviewing the literature. The Cochrane Risk of Bias Tool for Randomised Trials and an adapted version of the Downs and Black score were used to assess the quality of the included studies. A qualitative synthesis of five included studies is presented. A Forest Plot then presents quantitative data from four of the studies. A meta analysis did not take place. A generalised linear mixed effects model was applied to results from four of the studies.Results Five studies were included in the qualitative syntheses, three of the studies were randomised controlled trials, one was a prospective cohort study and one was a nested case-control in a cohort study. Two of the studies were assessed as high quality with three assessed as moderate quality. Odds ratios of children experiencing early childhood caries are reported for four studies demonstrating a reduced risk of early childhood caries in intervention groups compared to controls. A generalised linear mixed effects model using combined results from the four studies shows a reduced risk of developing early childhood caries in children up to the age of three years old whose mothers receive pre natal oral care. Above age three years the results of the modelling become non-significant. Based on the results of two studies the authors report a reduction in levels of S. mutans in the oral cavity of children whose mother had prenatal oral care.Conclusions The authors conclude that prenatal oral healthcare has a positive effect on incidence of early childhood caries and S. mutans carriage in children.

中文翻译:

产前口腔保健与儿童早期龋病预防之间是否存在关联?

数据来源数据库搜索包括Pubmed,Embase,Scopus,Web of Science,LILACS,Cochrane图书馆和ClinicalTrials.gov。研究选择该评价包括评估产前口腔保健对幼儿龋齿经历和/或口腔的影响的研究。变形链球菌的运输。该评价包括病例对照研究,回顾性或前瞻性队列研究,随机或非随机对照试验。体外研究,动物研究,文献综述,横断面研究和文献综述均被排除在外。数据提取和合成两名经过校准的独立审查者使用基于定义的纳入和排除标准的数据提取形式筛选了文献。给出了PRISMA流程图,显示了查阅文献的过程。随机试验的Cochrane偏倚风险工具和Downs和Black分数的改编版本用于评估纳入研究的质量。提出了五个纳入研究的定性综合。然后,森林图会提供来自四个研究的定量数据。没有进行荟萃分析。结果对4项研究的结果应用了广义线性混合效应模型。结果定性综合包括5项研究,3项研究为随机对照试验,1项为前瞻性队列研究,1项为病例对照研究。队列研究。其中两项研究被评估为高质量,三项研究被评估为中等质量。据报道,四项研究显示,患幼儿龋齿的儿童的几率比与对照组相比显示出干预组幼儿龋齿的风险降低。使用这四项研究的综合结果的广义线性混合效应模型表明,母亲接受产前口腔护理的三岁以下儿童发生幼儿龋齿的风险降低。超过三年的年龄,建模结果变得不重要。基于两项研究的结果,作者报告说,母亲进行了产前口腔护理的孩子的口腔中变形链球菌含量降低。结论作者得出结论,产前口腔保健对幼儿龋齿和龋齿的发生有积极影响。儿童携带变形链球菌。
更新日期:2019-11-18
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