Indirect treatment comparisons are useful to estimate relative treatment effects when head‐to‐head studies are not conducted. Statisticians at the National Centre for Pharmacoeconomics Ireland (NCPE) and Scottish Medicines Consortium (SMC) assess the clinical and cost‐effectiveness of new medicines as part of multidisciplinary teams. We describe some shared observations on areas where reporting of population‐adjustment indirect comparison methods is causing uncertainty in our recommendations to decision‐making committees when assessing reimbursement of medicines.

中文翻译：

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由于人口调整间接比较方法的报告不足，导致新药补偿建议存在困难。

当不进行头对头研究时，间接治疗比较可用于评估相对治疗效果。爱尔兰国家药物经济学中心（NCPE）和苏格兰医学联合会（SMC）的统计人员评估作为跨学科团队的一部分，新药的临床和成本效益。我们在报告人口调整间接比较方法导致评估药品报销时向决策委员会提出建议的不确定性的领域中描述了一些共同的看法。