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The relationship between erectile dysfunction and the Atherogenic Index of Plasma.
International Journal of Impotence Research ( IF 2.6 ) Pub Date : 2019-06-26 , DOI: 10.1038/s41443-019-0167-2
Emrah Ermis 1 , Sinem Ozbay Ozyilmaz 1 , Emre Salabas 2 , Cem Senol 3 , Mahir Cengiz 4 , Samir Allahverdiyev 1 , Hakan Ucar 1
Affiliation  

The objective of this study was to compare the Atherogenic Index of Plasma (AIP) values as indicators of subclinical atherosclerosis among 124 patients with erectile dysfunction, which was thought to be vasculogenic and 126 control subjects who had no erectile dysfunction, and to compare cardiac performance values between both the groups using exercise stress tests (EST). Erectile function was assessed using the International Index of Erectile Function (IIEF-5) questionnaire form. AIP values were studied and compared between patients with ED (IIEF < 22) and those without ED (IIEF > 22) using the log10 TG/HDL-C formula. In addition, the correlation between the severity of ED and AIP was investigated according to IIEF-5 scoring. Metabolic equivalent (MET) values, maximal heart rates (max HR), and heart rate recovery (HRR) were evaluated with effort tests. AIP values were significantly higher in the ED group than in the control group (0.45 ± 0.27, and 0.37 ± 0.27; p = 0.015). According to IIEF-5 scoring, AIP values increased as ED scores decreased. In the EST, MET score and max HR values were significantly lower in the ED group (METs: 11.1 ± 2.2, and 11.6 ± 2.2; p = 0.045; Max HR: 162.8 ± 6.1, and 165 ± 8.7; p = 0.019). Although not statistically significant, HRR values were lower in the ED group. Higher AIP values were found in the ED group, and a positive correlation was established between AIP and the severity of ED. In addition, lower performance during the EST and lower HRR values, again in the ED group, confirms cardiac interaction with ED. These results indicate the importance of referral of patients with ED from urology clinics to cardiology units for risk determination and cardiac assessment, even if they areasymptomatic.



中文翻译:

勃起功能障碍与血浆动脉粥样硬化指数之间的关系。

这项研究的目的是比较124例被认为具有血管生成功能的勃起功能障碍患者和126例没有勃起功能障碍的对照对象的血浆亚临床动脉粥样硬化指数(AIP)值作为亚临床动脉粥样硬化的指标,并比较心脏表现两组之间使用运动压力测试(EST)的数值。使用国际勃起功能指数(IIEF-5)问卷形式评估勃起功能。使用log 10对有ED(IIEF <22)和没有ED(IIEF> 22)的患者的AIP值进行研究和比较TG / HDL-C公式。此外,根据IIEF-5评分研究了ED和AIP严重程度之间的相关性。通过努力测试来评估代谢当量(MET)值,最大心率(max HR)和心率恢复(HRR)。ED组的AIP值显着高于对照组(0.45±0.27和0.37±0.27;p = 0.015)。根据IIEF-5评分,AIP值随着ED分数的降低而增加。在EST中,ED组的MET评分和最大HR值明显较低(MET:11.1±2.2和11.6±2.2; p = 0.045;最大HR:162.8±6.1和165±8.7; p= 0.019)。尽管无统计学意义,但ED组的HRR值较低。ED组的AIP值较高,并且AIP与ED的严重程度之间呈正相关。此外,在ED组中,EST期间较低的性能和较低的HRR值再次证实了与ED的心脏相互作用。这些结果表明,即使是有症状的ED患者,从泌尿科门诊转诊至心脏病学部门进行危险性测定和心脏评估也很重要。

更新日期:2019-11-18
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