The stage at which ribosomes are recruited to messenger RNAs (mRNAs) is an elaborate and highly regulated phase of protein synthesis. Upon completion of this step, a ribosome is positioned at an appropriate initiation codon and primed to synthesize the encoded polypeptide product. In most circumstances, this step commits the ribosome to translate the mRNA. We summarize the knowledge regarding the initiation factors implicated in this activity as well as review different mechanisms by which this process is conducted.

中文翻译：

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真核生物核糖体募集的组织原则。

核糖体被募集到信使RNA（mRNA）的阶段是蛋白质合成的复杂且高度受调控的阶段。完成该步骤后，将核糖体置于合适的起始密码子上并进行底漆以合成编码的多肽产物。在大多数情况下，该步骤使核糖体翻译mRNA。我们总结了有关此活动中涉及的引发因素的知识，并回顾了进行此过程的不同机制。