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Value of endoscopy for early diagnosis of pancreatic carcinoma
Digestive Endoscopy ( IF 5.0 ) Pub Date : 2019-07-25 , DOI: 10.1111/den.13467
Yasunobu Yamashita 1 , Masayuki Kitano 1 , Reiko Ashida 2
Affiliation  

Despite recent advances in diagnostic imaging modalities, most cases of pancreatic carcinoma are discovered at an unresectable stage, resulting in poor prognosis. Early diagnosis is essential to ensure curative treatment and improve the prognosis of pancreatic carcinoma. Imaging modalities with high diagnostic ability are necessary for the early diagnosis of pancreatic carcinoma. Endoscopic ultrasonography is a reliable and efficient diagnostic modality because it provides superior spatial resolution and should be incorporated into screening programs in patients at high risk of pancreatic carcinoma. Endoscopy facilitates cytopathological diagnosis based on samples collected via endoscopic ultrasonography‐guided fine‐needle aspiration and endoscopic retrograde cholangiopancreatography. Cytodiagnosis with endoscopic naso‐pancreatic drainage is useful in patients with carcinoma in situ. In this review, we highlight the potential role of endoscopy in the early diagnosis of pancreatic carcinoma. We provide an overview of the endoscopy tools used for the diagnosis of pancreatic carcinoma, discuss the diagnostic ability of these tools for small carcinomas and carcinomas in situ, and propose a strategy for endoscopy‐based screening of early pancreatic carcinoma.

中文翻译:


内镜检查对胰腺癌早期诊断的价值



尽管诊断成像方式最近取得了进展,但大多数胰腺癌病例是在不可切除阶段发现的,导致预后不良。胰腺癌的早期诊断对于确保治愈性治疗和改善预后至关重要。具有高诊断能力的成像方式对于胰腺癌的早期诊断是必要的。内窥镜超声检查是一种可靠且有效的诊断方式,因为它提供卓越的空间分辨率,应纳入胰腺癌高风险患者的筛查计划中。内窥镜有助于基于通过内镜超声引导的细针抽吸和内镜逆行胰胆管造影收集的样本进行细胞病理学诊断。内镜鼻胰引流术的细胞诊断对于原位癌患者很有用。在这篇综述中,我们强调内窥镜检查在胰腺癌早期诊断中的潜在作用。我们概述了用于诊断胰腺癌的内窥镜工具,讨论了这些工具对小癌和原位癌的诊断能力,并提出了基于内窥镜的早期胰腺癌筛查策略。
更新日期:2019-07-25
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