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The Potential Impact of Chikungunya Virus Outbreaks on Blood Transfusion.
Transfusion Medicine Reviews ( IF 2.7 ) Pub Date : 2019-06-20 , DOI: 10.1016/j.tmrv.2019.06.002
Hatsadee Appassakij 1 , Khachornsakdi Silpapojakul 2 , Charuporn Promwong 3 , Pairaya Rujirojindakul 1
Affiliation  

Chikungunya virus (CHIKV) is responsible for large periodic epidemics in both endemic and nonendemic areas where competent mosquitoes are present. Transmission of CHIKV by transfusion during explosive outbreaks has never been documented, and the true impact of CHIKV infection on blood transfusion during an outbreak is unknown. Considerations include not only transfusions in the active outbreak areas but also returning travelers to nonendemic areas. Because there are no documented cases of transfusion-transmitted CHIKV, there are no standard guidelines regarding transfusion policies during a chikungunya fever outbreak. We review current information from studies during outbreaks with the goal of estimating the potential effect of different blood safety interventions (eg, querying donors for possible CHIKV exposure, chikungunya fever–related symptoms, screening for CHIKV RNA).



中文翻译:

基孔肯雅热病毒爆发对输血的潜在影响。

基孔肯雅病毒(CHIKV)负责在存在有效蚊子的地方性和非地方性地区造成大规模的周期性流行病。从未爆发过爆发期间通过输血传播CHIKV的报道,而且在爆发期间CHIKV感染对输血的真正影响尚不清楚。考虑因素不仅包括活跃疫情爆发地区的输血,还包括旅行者返回非流行地区的方法。因为没有记录的输血传播CHIKV病例,所以没有关于基孔肯雅热爆发期间的输血政策的标准指南。我们回顾了暴发期间研究中的最新信息,目的是估计不同血液安全干预措施的潜在影响(例如,向捐赠者查询可能的CHIKV暴露,基孔肯雅热相关症状,

更新日期:2019-06-20
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