Pyroptotic cell death during endotoxemia causes death via unknown mechanisms. In this issue of Immunity, Wu et al. (2019) show that T3SS rod proteins or LPS induces inflammasome activation, macrophage pyroptosis, and accompanying tissue factor release, directly connecting inflammation to coagulation.

中文翻译：

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死亡即将到来，凝块变得越来越厚，光焦病助长了火势

内毒素血症期间的光热细胞死亡会通过未知机制导致死亡。在本期《免疫》中，Wu等人。（2019）显示T3SS杆蛋白或LPS诱导炎症小体激活，巨噬细胞焦化和伴随的组织因子释放，直接将炎症与凝血联系起来。