Surfaces within healthcare play a key role in the transmission of drug-resistant pathogens. Candida auris is an emerging multidrug-resistant yeast which can survive for prolonged periods on environmental surfaces. Here we show that the ability to form cellular aggregates increases survival after 14 days, which coincides with the upregulation of biofilm-associated genes. Additionally, the aggregating strain demonstrated tolerance to clinical concentrations of sodium hypochlorite and remained viable 14 days post treatment. The ability of C. auris to adhere to and persist on environmental surfaces emphasizes our need to better understand the biology of this fungal pathogen.

中文翻译：

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假丝酵母在体外表现出有弹性的生物膜特征：对环境持久性的影响。

医疗保健中的表面在耐药性病原体的传播中起着关键作用。黄金假丝酵母是一种新兴的具有多重耐药性的酵母，可以在环境表面上长期存活。在这里，我们显示了形成细胞聚集体的能力会在14天后增加存活率，这与生物膜相关基因的上调相吻合。另外，聚集的菌株表现出对临床次氯酸钠浓度的耐受性，并且在治疗后14天仍然可行。C. auris附着并在环境表面上持久存在的能力强调了我们需要更好地了解这种真菌病原体的生物学特性的需要。