Symptoms of heart failure (HF) are due in large part to elevation of left and/or right ventricular filling pressures. Although abnormal diastolic function is difficult to define, it contributes to the elevation of filling pressures. Tests that characterize aspects of diastolic function or structural changes associated with diastolic dysfunction, may help in establishing a diagnosis of HF, assessing prognosis, and guiding treatments. Individual echocardiographic parameters correlate weakly with LV (LV) filling pressures measured directly. However, a combination of multiple parameters improves accuracy for detection of elevated filling pressures. Serum natriuretic peptide levels are related to ventricular filling pressures and, when elevated, are a key diagnostic criterion for HF. Currently available evidence is not adequate to recommend serial echocardiographic studies or natriuretic peptide level measurements to assess changes in filling pressures or to guide HF therapy. Measurements of inferior vena cava size and dynamics have potential for identifying inadequate decongestion during episodes of acute decompensated HF but have not yet demonstrated utility in improving HF outcomes. Direct measurement of LV filling pressures using implanted pressure sensors is the only "diastolic assessment" thus far that has proven efficacy in reducing HF hospitalization rates.

中文翻译：

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我们应该检查舒张功能障碍吗？方式和频率？

心力衰竭（HF）的症状在很大程度上是由于左和/或右心室充盈压升高。尽管舒张功能异常很难定义，但它会导致充盈压升高。表征舒张功能或与舒张功能障碍相关的结构变化方面的测试，可能有助于建立心力衰竭的诊断，评估预后和指导治疗。各个超声心动图参数与直接测量的LV（LV）充盈压之间存在弱关联。然而，多个参数的组合提高了检测升高的填充压力的准确性。血清利钠肽水平与心室充盈压有关，当升高时，它是HF的关键诊断标准。当前可用的证据不足以推荐连续超声心动图研究或利钠肽水平测量以评估充盈压的变化或指导HF治疗。下腔静脉的大小和动态变化的测量值有可能在急性失代偿性HF发作期间识别充血不足，但尚未证明可用于改善HF结局。迄今为止，使用植入式压力传感器直接测量左室充盈压是唯一已被证实可有效降低心衰住院率的“舒张期评估”。下腔静脉的大小和动态变化的测量值有可能在急性失代偿性HF发作期间识别充血不足，但尚未证明可用于改善HF结局。迄今为止，使用植入式压力传感器直接测量左室充盈压是唯一已被证实可有效降低心衰住院率的“舒张期评估”。下腔静脉的大小和动态变化的测量值有可能在急性失代偿性HF发作期间识别充血不足，但尚未证明可用于改善HF结果。迄今为止，使用植入式压力传感器直接测量左室充盈压是唯一已被证实可有效降低心衰住院率的“舒张期评估”。