Chromatographic separation has been widely applied in various fields, such as chemical engineering, precision medicine, energy, and biology. Because chromatographic separation is based on differential partitioning between the mobile phase and stationary phase and affected by band dispersion and mass transfer resistance from these two phases, the materials used as the stationary phase play a decisive role in separation performance. In this review, we discuss the design of separation materials to achieve the separation with high efficiency and high resolution and highlight the well-defined materials with uniform pore structure and unique properties. The achievements, recent developments, challenges, and future trends of such materials are discussed. Furthermore, the surface functionalization of separation ma-terials for further improvement of separation performance is reviewed. Finally, future research directions and the challenges of chromatographic separation are presented.

中文翻译：

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高效色谱分离的精密材料。

色谱分离已广泛应用于化学工程，精密医学，能源和生物学等各个领域。因为色谱分离是基于流动相和固定相之间的差异分配，并且受这两个相的谱带分散和传质阻力的影响，所以用作固定相的材料在分离性能中起着决定性的作用。在这篇综述中，我们讨论了分离材料的设计，以实现高效和高分辨率的分离，并重点介绍具有均匀孔结构和独特性能的定义明确的材料。讨论了这些材料的成就，最新发展，挑战和未来趋势。此外，综述了用于进一步提高分离性能的分离材料的表面功能化。最后，提出了未来的研究方向和色谱分离的挑战。