There has been a long history of the use of mathematics in genetics, ranging from the use of statistics to analyse genetic data to genetic models of evolutionary processes. Contemporary research into the genomic basis of disease and complex traits exemplifies the importance of statistical methods in genetics. Some examples of the development and application of population genetic models are described, which are intended to highlight the utility of such models for understanding variation and evolution in natural populations. The effects of selection on variability at sites linked to the targets of selection illustrate how fruitful interactions between theory and data can be.

中文翻译：

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为遗传学中的算术辩护

数学在遗传学中的应用有着悠久的历史，从使用统计学来分析遗传数据到进化过程的遗传模型。当代对疾病和复杂性状的基因组基础的研究例证了遗传学中统计方法的重要性。描述了群体遗传模型的发展和应用的一些例子，旨在强调此类模型在理解自然群体变异和进化方面的实用性。选择对与选择目标相关的位点变异性的影响说明了理论和数据之间的相互作用是多么富有成效。