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Patterns in the genome
Heredity ( IF 3.1 ) Pub Date : 2019-06-12 , DOI: 10.1038/s41437-019-0220-4
Wendy A Bickmore 1
Affiliation  

The human genome is not randomly organised, with respect to both the linear organisation of the DNA sequence along chromosomes and to the spatial organisation of chromosomes in the cell nucleus. Here I discuss how these patterns of sequence organisation were first discovered by molecular biologists and how they relate to the patterns revealed decades earlier by cytogeneticists and manifest as chromosome bands.

中文翻译:

基因组中的模式

就 DNA 序列沿染色体的线性组织和细胞核中染色体的空间组织而言,人类基因组不是随机组织的。在这里,我将讨论这些序列组织模式是如何首先被分子生物学家发现的,以及它们与细胞遗传学家几十年前揭示并表现为染色体条带的模式之间的关系。
更新日期:2019-06-12
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