Abstract While laser sintering (LS) processes are typically optimised towards denser powder beds, our approach is different as we investigate the use of non-dense powder beds made of porous composite powder materials of polylactide-co-glycolide (PLGA) and bioactive glass (BG) 45S5. Powders were produced via solid-in-oil-in-water emulsion with modified BG as porogen and changing PLGA:BG ratios with up to 50 wt% of BG. Characterisation was done using scanning electron microscope (SEM), Fourier-transform infrared spectroscopy (FTIR), X-ray fluorescence (XRF), thermal gravimetric analysis (TG), powder packing and flow, particle-size distribution (PSD) and X-ray tomography. The microparticles showed varying degrees of sphericity, porosity and specific surface area (SSA), while the BG porogen could be incorporated into or onto the foamed polymer. Powders were used for LS and gave parts with an overall porosity of ~ 75%. Our special approach might be interesting for multi-material LS for real biomimetic scaffolds with tailored hierarchical pore structures.

中文翻译：

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评估用于支架激光烧结的多孔聚丙交酯-共-乙交酯/生物活性玻璃复合微球粉末

摘要 虽然激光烧结 (LS) 工艺通常针对更致密的粉末床进行优化，但我们的方法有所不同，因为我们研究了使用由聚丙交酯-共-乙交酯 (PLGA) 和生物活性玻璃制成的多孔复合粉末材料制成的非致密粉末床。 BG）45S5。粉末是通过水包油包固体乳液生产的，其中改性 BG 作为致孔剂，并改变 PLGA:BG 比率，BG 的重量百分比高达 50%。使用扫描电子显微镜 (SEM)、傅里叶变换红外光谱 (FTIR)、X 射线荧光 (XRF)、热重分析 (TG)、粉末堆积和流动、粒度分布 (PSD) 和 X-射线断层扫描。微粒表现出不同程度的球形度、孔隙率和比表面积 (SSA)，而 BG 致孔剂可以结合到泡沫聚合物中或结合到泡沫聚合物上。粉末用于 LS 并得到总孔隙率约为 75% 的部件。我们的特殊方法可能对具有定制分层孔隙结构的真实仿生支架的多材料 LS 感兴趣。