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Current and Future Considerations in the Use of Mechanical Circulatory Support Devices: An Update, 2008-2018.
Annual Review of Biomedical Engineering ( IF 9.7 ) Pub Date : 2019-06-05 , DOI: 10.1146/annurev-bioeng-062117-121120
Marc A Simon 1, 2, 3 , Timothy N Bachman 1, 2, 3 , John Watson 4 , J Timothy Baldwin 5 , William R Wagner 2, 3, 6, 7 , Harvey S Borovetz 2, 3, 6, 7
Affiliation  

Our review in the 2008 volume of this journal detailed the use of mechanical circulatory support (MCS) for treatment of heart failure (HF). MCS initially utilized bladder-based blood pumps generating pulsatile flow; these pulsatile flow pumps have been supplanted by rotary blood pumps, in which cardiac support is generated via the high-speed rotation of computationally designed blading. Different rotary pump designs have been evaluated for their safety, performance, and efficacy in clinical trials both in the United States and internationally. The reduced size of the rotary pump designs has prompted research and development toward the design of MCS suitable for infants and children. The past decade has witnessed efforts focused on tissue engineering-based therapies for the treatment of HF. This review explores the current state and future opportunities of cardiac support therapies within our larger understanding of the treatment options for HF.

中文翻译:

使用机械循环支撑设备的当前和将来注意事项:更新,2008-2018年。

我们在该期刊2008年的评论中详细介绍了使用机械循环支持(MCS)治疗心力衰竭(HF)的方法。MCS最初利用了基于膀胱的血泵来产生搏动性血流。这些脉动血流泵已经被旋转血泵所取代,在旋转血泵中,通过计算设计的叶片的高速旋转产生了心脏支持。在美国和国际上,已经在临床试验中对不同的旋转泵设计的安全性,性能和功效进行了评估。旋转泵设计尺寸的减小促使人们对适用于婴幼儿的MCS设计进行了研究和开发。在过去的十年中,目睹了针对基于组织工程的心力衰竭治疗的努力。
更新日期:2020-04-21
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