Postorgasmic illness syndrome (POIS) is a rare condition that affects men and about which little is known. According to Waldinger and colleagues, men with POIS fulfill three or more of five preliminary diagnostic criteria regarding symptoms, time to onset, setting, duration, and spontaneous disappearance. We conducted a self-report study to assess, for the first time, the validity of these criteria. One hundred and twenty-seven men with self-reported POIS have completed the survey, making this the largest study of such men to date. Almost all respondents fulfill a majority of the criteria for POIS; a large minority fulfills all five criteria. Almost all respondents always experience symptoms after ejaculating in at least one ejaculatory setting (sex, masturbation, or nocturnal emission), though only a small majority fulfill the criterion that symptoms occur after all ejaculations because a large minority always experience symptoms in one setting but not always in another. The most common symptom cluster from the criteria, involving fatigue, irritation, and concentration difficulties, is always experienced by 80% of respondents. Median symptom severity is 8 on a 0-10 scale. While almost all men with POIS fulfill a majority of the preliminary diagnostic criteria, there is room for refining some of the criteria.

中文翻译：

---

首次评估了性高潮后综合症（POIS）唯一诊断标准的有效性。

性高潮后综合症（POIS）是一种罕见的疾病，会影响男性，对此鲜为人知。根据Waldinger及其同事的说法，POIS男性符合五个初步诊断标准中的三个或三个以上，这些标准涉及症状，发作时间，环境，持续时间和自发消失。我们进行了一项自我报告研究，以首次评估这些标准的有效性。127名自我报告POIS的男性已完成调查，这是迄今为止此类男性最大的研究。几乎所有受访者都符合POIS的大多数标准；少数人符合所有五个条件。几乎所有受访者在至少一种射精情况下（性，手淫或夜尿）射精后总会出现症状，尽管只有极少数能满足所有射精后都会出现症状的标准，因为一小部分人总是会在一种情况下出现症状，而并非总是在另一种情况下。该标准中最常见的症状群包括疲劳，刺激和集中困难，始终有80％的受访者经历过。症状严重程度的中位数是0-10级，为8。尽管几乎所有患有POIS的男性都符合大多数初步诊断标准，但仍有一些地方可以完善一些标准。症状严重程度的中位数是0-10级，为8。尽管几乎所有患有POIS的男性都符合大多数初步诊断标准，但仍有一些地方可以完善一些标准。症状严重程度的中位数是0-10，分为8级。尽管几乎所有患有POIS的男性都符合大多数初步诊断标准，但仍有一些地方可以完善一些标准。