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Root extracellular traps versus neutrophil extracellular traps in host defence, a case of functional convergence?
Biological Reviews ( IF 11.0 ) Pub Date : 2019-05-27 , DOI: 10.1111/brv.12522
Azeddine Driouich 1, 2 , Carine Smith 3 , Marc Ropitaux 1, 2 , Marie Chambard 1, 2 , Isabelle Boulogne 1, 2 , Sophie Bernard 1, 2 , Marie-Laure Follet-Gueye 1, 2 , Maïté Vicré 1, 2 , John Moore 4
Affiliation  

The root cap releases cells that produce massive amounts of mucilage containing polysaccharides, proteoglycans, extracellular DNA (exDNA) and a variety of antimicrobial compounds. The released cells – known as border cells or border‐like cells – and mucilage secretions form networks that are defined as root extracellular traps (RETs). RETs are important players in root immunity. In animals, phagocytes are some of the most abundant white blood cells in circulation and are very important for immunity. These cells combat pathogens through multiple defence mechanisms, including the release of exDNA‐containing extracellular traps (ETs). Traps of neutrophil origin are abbreviated herein as NETs. Similar to phagocytes, plant root cap‐originating cells actively contribute to frontline defence against pathogens. RETs and NETs are thus components of the plant and animal immune systems, respectively, that exhibit similar compositional and functional properties. Herein, we describe and discuss the formation, molecular composition and functional similarities of these similar but different extracellular traps.

中文翻译:

宿主防御中的根细胞外陷阱与中性粒细胞细胞外陷阱,功能收敛的案例?

根帽释放的细胞会产生大量含有多糖、蛋白聚糖、细胞外 DNA (exDNA) 和各种抗菌化合物的粘液。释放的细胞(称为边界细胞或边界样细胞)和粘液分泌物形成被定义为根细胞外陷阱 (RET) 的网络。RET 是根免疫的重要参与者。在动物中,吞噬细胞是循环中最丰富的白细胞之一,对免疫非常重要。这些细胞通过多种防御机制对抗病原体,包括释放含有 exDNA 的细胞外陷阱 (ET)。中性粒细胞来源的陷阱在本文中缩写为 NET。与吞噬细胞类似,植物根冠起源细胞积极参与防御病原体的前线防御。因此,RET 和 NET 分别是植物和动物免疫系统的组成部分,它们表现出相似的组成和功能特性。在这里,我们描述和讨论了这些相似但不同的细胞外陷阱的形成、分子组成和功能相似性。
更新日期:2019-05-27
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