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Candida albicans dwelling in the mammalian gut.
Current Opinion in Microbiology ( IF 5.9 ) Pub Date : 2019-05-25 , DOI: 10.1016/j.mib.2019.04.007
J Christian Pérez 1
Affiliation  

The yeast Candida albicans inhabits the gastrointestinal tract of most healthy adults, seemingly living there as a harmless commensal. The fungus on occasion disseminates from the gut to other internal organs causing life-threatening infections. Here, I review some of the most exciting advances in the study of gut colonization by C. albicans in the last few years. These developments highlight the close interplay between C. albicans and cohabiting microbes, the responses that commensal fungi elicit from the mammalian host, and the genetic determinants that allow the fungus to thrive in such a crowded and demanding ecosystem.



中文翻译:

白色念珠菌居住在哺乳动物的肠道中。

白色念珠菌酵母菌居住在大多数健康成年人的胃肠道中,看起来像是无害的食物。真菌有时会从肠道扩散到其他内部器官,从而导致威胁生命的感染。在这里,我回顾了最近几年白念珠菌对肠道定植的研究中一些最令人振奋的进展。这些发展突显了白色念珠菌与同居微生物之间的紧密相互作用,共生真菌从哺乳动物宿主中引起的反应以及使真菌在如此拥挤而苛刻的生态系统中壮成长的遗传决定因素。

更新日期:2019-11-18
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