Single-cell transcriptome profiling has enabled high-resolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to interact with tissue components in the lung during development and fibrotic lung disease.

中文翻译：

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以单细胞分辨率解剖肺发育和纤维化。

单细胞转录组谱分析已使在发育，健康和疾病过程中对组织中细胞群体的高分辨率分析成为可能。最近的研究创新性地利用了单细胞RNA测序（scRNAseq）来研究在发育和纤维化性肺病期间允许免疫细胞与肺中组织成分相互作用的机制。