In the modern era, the use of sustainable, environmentally friendly alternatives for removal of recalcitrant pollutants in streams resulting from industrial processes is of key importance. In this context, biodegradation of phenolic compounds, pharmaceuticals and dyes in wastewater by using oxidoreductases offers numerous benefits. Tremendous research efforts have been made to develop novel, hybrid strategies for simultaneous immobilization of oxidoreductase and removal of toxic compounds. The use of support materials with the options for combining enzyme immobilization with adsorption technology focused on phenolic pollutants and products of biocatalytic conversion seems to be of particular interest. Application of enzymatic reactors based on immobilized oxidoreductases for coupling enzyme-aided degradation and membrane separation also attract still growing attention. However, prior selection of the most suitable support/sorbent material and/or membrane as well as operational mode and immobilization technique is required in order to achieve high removal efficiency. Thus, in the framework of this review, we present an overview of the impact of support/sorbent material on the catalytic properties of immobilized enzymes and sorption of pollutants as well as parameters of membranes for effective bioconversion and separation. Finally, future perspectives of the use of processes combining enzyme immobilization and sorption technology as well as application of enzymatic reactors for removal of environmental pollutants are discussed.

在现代时代，使用可持续的，环境友好的替代品来去除工业过程中产生的有害污染物是至关重要的。在这种情况下，通过使用氧化还原酶对废水中的酚类化合物，药物和染料进行生物降解具有许多好处。为了开发新颖的混合策略同时固定氧化还原酶和去除有毒化合物，已经进行了大量的研究工作。使用支持材料以及将酶固定化与针对酚类污染物和生物催化转化产物的吸附技术相结合的选项似乎特别受关注。基于固定化氧化还原酶的酶反应器在酶辅助降解和膜分离之间的耦合应用也引起了越来越多的关注。然而，为了获得高去除效率，需要预先选择最合适的载体/吸附剂材料和/或膜以及操作模式和固定技术。因此，在本综述的框架内，我们概述了载体/吸附剂材料对固定化酶催化性能和污染物吸附以及膜参数的影响，以进行有效的生物转化和分离。最后，讨论了使用酶固定化和吸附技术相结合的方法的未来观点以及酶反应器在去除环境污染物中的应用。