Mast-cell-nerve interactions play an integral role in itch and inflammation. Meixiong et al. (2019) show that the receptors MRGPRB2 and FcεRI mediate distinct types of mast cell activation and nerve interactions and that mast cell activation through MRGPRB2 drives itch in allergic contact dermatitis.

中文翻译：

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肥大细胞进入瘙痒神经

肥大细胞-神经相互作用在瘙痒和炎症中起着不可或缺的作用。Meixiong等。（2019）表明，受体MRGPRB2和FcεRI介导肥大细胞活化和神经相互作用的不同类型，并且通过MRGPRB2肥大细胞活化驱使过敏性接触性皮炎发痒。