During the process of regeneration, a switch in the transcription program occurs in cells that contribute to the reconstruction of the missing tissue. Early signals released upon damage are integrated into the chromatin of responding cells to change its activity and function. Changes in chromatin dynamics result in transcriptional reprogramming, this is the coordinated regulation of expression of a specific subset of genes required for the regeneration process. Here we summarize changes in gene expression and chromatin dynamics that occurs during the process of regeneration of Drosophila imaginal discs.

中文翻译：

---

再生上皮细胞的染色质动力学：果蝇假想盘的教训。

在再生过程中，转录程序中的开关发生在有助于缺失组织重建的细胞中。损伤后释放的早期信号被整合到反应细胞的染色质中，以改变其活性和功能。染色质动力学的变化导致转录重编程，这是再生过程所需的特定基因子集表达的协调调节。在这里，我们总结了果蝇假想盘再生过程中发生的基因表达和染色质动力学变化。