Crystallographic structures of protein complexes are essential to develop proteomic and structural biology methods, as prediction of protein–protein interaction (PPI) sites and protein–protein docking. Such structures can aid the development of protein complexation inhibitors. Complex DataBase (CDB), accessible at www.jct-bioinfo.com/cdb/search, is a database web application for heterodimeric protein crystallographic complexes along with the crystallographic structures of each individual unbound protein. Direct access to crystallographic structures of protein complexes, along with provided annotations, can serve as starting point for constructing new experimental protein complexes sets of any type, for protein binding studies, and the development and evaluation of PPIs prediction methods.

中文翻译：

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CDB-蛋白质异二聚体复合物数据库

蛋白质复合物的晶体结构对于蛋白质组学和结构生物学方法的发展至关重要，因为可以预测蛋白质-蛋白质相互作用（PPI）位点和蛋白质-蛋白质对接。这样的结构可以帮助蛋白质复合抑制剂的发展。复杂数据库（CDB），可在www.jct-bioinfo.com/cdb/search上访问，是用于异二聚体蛋白质晶体复合物以及每个单独的未结合蛋白质的晶体结构的数据库Web应用程序。直接访问蛋白质复合物的晶体结构以及提供的注释，可以作为构建任何类型的新实验蛋白质复合物集，进行蛋白质结合研究以及开发和评估PPI预测方法的起点。