Mental disorders are increasingly conceptualized as biomedical diseases, explained as manifestations of genetic and neurobiological abnormalities. Here, we discuss changes in the dominant explanatory accounts of psychopathology that have occurred over time and the driving forces behind these shifts, lay out some real-world evidence for the increasing ascendancy of biomedical explanations, and provide an overview of the types of attitudes and beliefs that may be affected by them. We examine theoretical and conceptual models that are relevant to understanding how biomedical conceptualizations might affect attitudes and beliefs about mental disorders, and we review some empirical evidence that bears on this question. Finally, we examine possible strategies for combatting potential negative effects of biomedical explanations and discuss important conclusions and directions for future research.

中文翻译：

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心理病理学的生物医学解释及其对精神障碍的态度和信念的含义。

精神疾病越来越被概念化为生物医学疾病，被解释为遗传和神经生物学异常的表现。在这里，我们讨论了随着时间推移发生的心理病理学主要解释性解释的变化以及这些变化背后的驱动力，为生物医学解释的日益普及提供了一些现实证据，并概述了态度和态度的类型。可能会受到他们影响的信念。我们研究了与理解生物医学概念化如何影响精神疾病的态度和信念有关的理论和概念模型，并且我们回顾了有关该问题的一些经验证据。最后，