A two‐component matrix of 2‐nitrophloroglucinol (2‐NPG) and silica nanoparticles was used for matrix‐assisted laser desorption ionization (MALDI) mass spectrometry imaging of high‐charge‐state biomolecules in tissue. Potential advantages include increased effective mass range and efficiency of fragmentation.

中文翻译：

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用于组织基质辅助激光解吸电离成像中多重充电的纳米颗粒共基质

2-硝基苯三醇 (2-NPG) 和二氧化硅纳米粒子的双组分基质用于组织中高电荷态生物分子的基质辅助激光解吸电离 (MALDI) 质谱成像。潜在优势包括增加有效质量范围和碎裂效率。