Contextual information is used to support and organize episodic memory. Prior research has reliably shown memory deficits in psychosis; however, little research has characterized how this population uses contextual information during memory recall. We employed an approach founded in a computational framework of free recall to quantify how individuals with first episode of psychosis (FEP, N = 97) and controls (CON, N = 55) use temporal and semantic context to organize memory recall. Free recall was characterized using the Hopkins Verbal Learning Test-Revised (HVLT-R). We compared FEP and CON on three measures of free recall: proportion recalled, temporal clustering, and semantic clustering. Measures of temporal/semantic clustering quantified how individuals use contextual information to organize memory recall. We also assessed to what extent these measures relate to antipsychotic use and differentiated between different types of psychosis. We also explored the relationship between these measures and intelligence. In comparison to CON, FEP had reduced recall and less temporal clustering during free recall (p < 0.05, Bonferroni-corrected), and showed a trend towards greater semantic clustering (p = 0.10, Bonferroni-corrected). Within FEP, antipsychotic use and diagnoses did not differentiate between free recall accuracy or contextual organization of memory. IQ was related to free recall accuracy, but not the use of contextual information during recall in either group (p < 0.05, Bonferroni-corrected). These results show that in addition to deficits in memory recall, FEP differed in how they organize memories compared to CON.

上下文信息用于支持和组织情节记忆。先前的研究已经可靠地显示出精神病患者的记忆缺陷。然而，很少有研究描述这种人群在记忆回忆期间如何使用上下文信息。我们采用了一种在自由召回的计算框架中建立的方法来量化患有首发精神病（FEP，N  = 97）和对照（CON，N = 55）使用时态和语义上下文来组织记忆调用。使用霍普金斯语言学习测验修订版（HVLT-R）来表征自由召回。我们将FEP和CON在三种自由回想度量上进行了比较：比例回想，时间聚类和语义聚类。时间/语义聚类的度量量化了个人如何使用上下文信息来组织记忆回忆。我们还评估了这些措施在多大程度上与抗精神病药物的使用有关，并区分了不同类型的精神病。我们还探讨了这些措施与情报之间的关系。与CON相比，FEP减少了自由召回期间的回忆和较少的时间聚类（p  <0.05，Bonferroni校正），并显示了更大的语义聚类趋势（p = 0.10，经Bonferroni校正）。在FEP中，抗精神病药的使用和诊断在自由回忆的准确性或上下文的记忆组织之间没有区别。智商与自由召回的准确性有关，但与任一组的召回期间的情境信息使用无关（p  <0.05，经Bonferroni校正）。这些结果表明，与记忆缺陷相比，FEP与CON相比在记忆组织方式上有所不同。