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The impact of surgery for lower urinary tract symptoms/benign prostatic enlargement on both erectile and ejaculatory function: a systematic review.
International Journal of Impotence Research ( IF 2.8 ) Pub Date : 2019-04-17 , DOI: 10.1038/s41443-019-0140-0
Paolo Verze 1 , Gianluigi Califano 1 , Ioannis Sokolakis 2 , Giorgio Ivan Russo 3 , Georgios Hatzichristodoulou 2 , Gennaro Musi 4 , Massimiliano Creta 1 ,
Affiliation  

We performed a systematic review of studies evaluating the impact of surgery for lower urinary tract symptoms suggestive of benign prostate enlargement (LUTS/BPE) on both erectile and ejaculatory functions. In June 2018, we searched for randomized controlled trials (RCTs) published between 1998 and 2018 in which both functions were assessed using questionnaires. Overall, 15 studies were identified. Pre-operatively, mean International Index of Erectile Function −5 (IIEF-5) and mean IIEF—Erectile Function (EF) scores ranged from 13.3 to 20.8, and from 13.7 to 22.3, respectively. At follow-up evaluations, mean IIEF-5 and mean IIEF-EF scores did not significantly vary (13.4 to 20.7 and 14.4 to 24.3, respectively). Mean baseline Male Sexual Health Questionnaire- Ejaculatory Disease function score at baseline and follow-up evaluations ranged from 8.7 to 10.6, and from 4.9 to 11.9, respectively. Ejaculatory function significantly worsened in three studies after transurethral resection of the prostate and significantly improved in 2 studies after prostate urethral lift implant. In conclusions, available RCTs evaluating both erectile and ejaculatory functions after surgical procedures for LUTS/BPE fail to demonstrate significant variations in terms of erectile function scores while providing significant variations of ejaculatory function scores that are heterogeneous depending on the procedure adopted.



中文翻译:

下尿路症状/前列腺增生对勃起和射精功能的影响:系统评价。

我们对研究评估下尿路症状提示前列腺增生(LUTS / BPE)对勃起和射精功能的影响进行了系统的研究回顾。在2018年6月,我们搜索了1998年至2018年之间发布的随机对照试验(RCT),其中两种功能均使用问卷进行了评估。总体而言,确定了15项研究。术前,国际勃起功能指数-5(IIEF-5)和平均IIEF-勃起功能(EF)评分分别为13.3至20.8和13.7至22.3。在随访评估中,IIEF-5平均得分和IIEF-EF平均得分没有显着差异(分别为13.4至20.7和14.4至24.3)。基线男性性健康问卷平均水平-射精病基线和随访评估范围为8。从7到10.6,从4.9到11.9。经尿道前列腺切除术后的三项研究中,射精功能显着恶化,经前列腺尿道举起植入物后的两项研究中,射精功能显着改善。综上所述,对LUTS / BPE手术后评估勃起功能和射精功能的可用RCT无法证明勃起功能评分有显着差异,而射精功能得分却存在显着差异,具体取决于所采用的手术方法。

更新日期:2019-05-16
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