Hemostasis and immunity were long considered entirely separate entities. In this issue of Immunity, Burzynski et al. (2019) find that thrombin, the key enzyme within the coagulation cascade, activates IL-1α, a central pleiotropic pro-inflammatory cytokine, to promote wound healing and platelet production following ectoderm injury.

中文翻译：

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凝血酶：加速固有免疫力的油门踏板

长期以来，止血和免疫一直被认为是完全独立的实体。在本期《免疫》中，Burzynski等人。（2019）发现凝血酶是凝血级联反应中的关键酶，它激活IL-1α（一种中央多效性促炎细胞因子），以促进外胚层损伤后伤口的愈合和血小板的产生。