The surface of nuclear waste container will be completely wetted by the groundwater infiltrating through the bentonite or concrete buffer after the closure of its deep geological disposal. Because of its excellent corrosion resistance, titanium is one of the candidates for the container materials for high-level nuclear waste (HLNW) disposal. However, once oxygen depleted in the large time scale deep geological disposal, titanium container will suffer from hydrogen embrittlement (HE). Therefore, in order to predict the potential danger of the HLNW container caused by HE, the hydrogen entry into titanium was studied at different temperatures in simulated deep geological environment of Beishan, which is the preselected HLNW disposal area in China. Devanathan-Stachurski cell methods were firstly implemented in measuring apparent hydrogen diffusivity in titanium with hydrides being formed during hydrogen charging at low temperature ranges (298–373 K). Given the characteristic of the Devanathan-Stachurski cell method's capable of getting apparent diffusivity with combined influencing factors easily, the technique provides a simple way to measure the parameter that is necessary for the estimation of hydrogen penetration depth, facilitating the design of HLNW containers.