BACKGROUND Research prioritisation can help identify clinically relevant questions and encourage high-quality, patient-centred research. Delphi methodology aims to develop consensus opinion within a group of experts, with recent Delphi projects helping to define the research agenda and funding within several medical and surgical specialties. METHODS All members of the Association of Upper Gastrointestinal Surgeons (AUGIS) were asked to submit clinical research questions using an online survey (Phase 1). Two consecutive rounds of Delphi prioritisation by multidisciplinary HPB healthcare professionals (Phase 2) were undertaken to establish a final list of the most highly prioritised research questions. A multidisciplinary steering committee analysed the results of each phase. RESULTS Ninety-three HPB-focussed questions were identified in Phase 1, with thirty-seven questions of sufficient priority to enter a further prioritisation round. A final group of 11 questions considered highest priority were identified. The most highly ranked research questions related to treatment pathways, operative strategies and the impact of HPB procedures on quality of life, particularly for malignant disease. CONCLUSION Expert consensus has identified research priorities within the UK HPB surgical community over the coming years. Funding applications, to establish well-designed, high quality collaborative research are now required to address these questions.

中文翻译：

---

在英国使用改良的Delphi方法开发HPB手术的研究重点。

背景技术研究的优先次序可以帮助确定临床上相关的问题，并鼓励高质量，以患者为中心的研究。Delphi方法论旨在在一组专家中形成共识，最近的Delphi项目帮助定义了医学和外科专业领域的研究议程和资金。方法要求上消化道外科医师协会（AUGIS）的所有成员使用在线调查（阶段1）提交临床研究问题。多学科HPB医疗保健专业人员（阶段2）进行了两轮Delphi优先排序，以建立最高度优先研究问题的最终清单。一个多学科指导委员会分析​​了每个阶段的结果。结果在第一阶段中确定了93个针对HPB的问题 有37个优先级足够高的问题，可以进入进一步的优先级排序。最终确定了11个被认为是最高优先级的问题。排名最高的研究问题与治疗途径，手术策略以及HPB程序对生活质量（尤其是恶性疾病）的生活质量的影响有关。结论专家共识已确定了未来几年英国HPB外科界的研究重点。解决这些问题现在需要资金申请，以建立设计良好的高质量协作研究。手术策略以及HPB程序对生活质量（尤其是恶性疾病）的生活质量的影响。结论专家共识已确定了未来几年英国HPB外科界的研究重点。解决这些问题现在需要资金申请，以建立设计良好的高质量协作研究。手术策略以及HPB程序对生活质量（尤其是恶性疾病）的生活质量的影响。结论专家共识已确定了未来几年英国HPB外科界的研究重点。解决这些问题现在需要资金申请，以建立设计良好的高质量协作研究。