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Diabetic cardiomyopathy - A comprehensive updated review.
Progress in Cardiovascular Diseases ( IF 5.6 ) Pub Date : 2019-03-25 , DOI: 10.1016/j.pcad.2019.03.003
Ghulam Murtaza 1 , Hafeez Ul Hassan Virk 2 , Muhammad Khalid 1 , Carl J Lavie 3 , Hector Ventura 3 , Debabrata Mukherjee 4 , Vijay Ramu 1 , Sukhdeep Bhogal 1 , Gautam Kumar 5 , Madhan Shanmugasundaram 6 , Timir K Paul 1
Affiliation  

Diabetes causes cardiomyopathy and increases the risk of heart failure independent of hypertension and coronary heart disease. This condition called "Diabetic Cardiomyopathy" (DCM) is becoming a well- known clinical entity. Recently, there has been substantial research exploring its molecular mechanisms, structural and functional changes, and possible development of therapeutic approaches for the prevention and treatment of DCM. This review summarizes the recent advancements to better understand fundamental molecular abnormalities that promote this cardiomyopathy and novel therapies for future research. Additionally, different diagnostic modalities, up to date screening tests to guide clinicians with early diagnosis and available current treatment options has been outlined.

中文翻译:

糖尿病心肌病 - 全面更新的评论。

糖尿病会导致心肌病并增加心力衰竭的风险,而与高血压和冠心病无关。这种称为“糖尿病心肌病”(DCM) 的病症正在成为众所周知的临床实体。最近,有大量研究探索其分子机制、结构和功能变化,以及预防和治疗 DCM 治疗方法的可能发展。本综述总结了最近的进展,以更好地了解促进这种心肌病的基本分子异常和未来研究的新疗法。此外,还概述了不同的诊断方式、最新的筛查测试,以指导临床医生进行早期诊断和可用的当前治疗选择。
更新日期:2019-03-25
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