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Exosomes Exercise Inhibition of Anti-Tumor Immunity during Chemotherapy
Immunity ( IF 32.4 ) Pub Date : 2019-03-19 , DOI: 10.1016/j.immuni.2019.02.019
Valerie S. LeBleu , Raghu Kalluri

Exosomes are nano-sized extracellular vesicles that contain DNA, RNA, proteins, and lipids. Exosomes likely participate in facilitating intercellular communication and tumor growth. In this issue of Immunity, Zhang et al. (2019) report on the metabolic activity of B cell-derived exosomes in facilitating the suppression of cytotoxic T cells.



中文翻译:

外泌体在化疗期间抑制抗肿瘤免疫力

外泌体是含有DNA,RNA,蛋白质和脂质的纳米级细胞外囊泡。外泌体可能参与促进细胞间通讯和肿瘤生长。在本期《免疫》中,Zhang等人。(2019)报告了B细胞来源的外泌体在促进抑制细胞毒性T细胞方面的代谢活性。

更新日期:2019-03-19
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