OBJECTIVE Treatment for childhood anxiety disorders is insufficient in many cases. Parent involvement has been examined to augment child-based cognitive-behavioral therapy (CBT), but no studies have compared the efficacy of stand-alone parent-based treatment to CBT. Research implicates family accommodation in the maintenance and course of childhood anxiety. Supportive Parenting for Anxious Childhood Emotions (SPACE) is a parent-based treatment that reduces accommodation of childhood anxiety. This study compared SPACE to CBT in a noninferiority trial. METHOD Participants were children with primary anxiety disorders (N = 124; 7-14 years of age; 53% female participants; 83% white), randomly assigned to either SPACE (n = 64) with no direct child-therapist contact, or CBT (n = 60) with no parent treatment. A total of 97 participants (78%) completed all treatment sessions and assessments. Attrition did not differ significantly between groups. Primary anxiety outcomes included diagnostic interview and clinician-rated scales. Secondary outcomes included parent and child ratings of anxiety severity, family accommodation, and parenting stress. Noninferiority margins were determined based on statistical and clinical considerations. Change in family accommodation and parenting stress were examined using mixed models analyses. RESULTS SPACE was noninferior, relative to CBT, on primary and secondary anxiety outcomes, and based on ratings provided by independent evaluators, parents, and children. Family accommodation and parenting stress were significantly reduced in both treatments, with significantly greater reduction in family accommodation following SPACE compared to CBT. Treatment credibility and satisfaction were high. CONCLUSION SPACE is an acceptable and efficacious treatment for childhood anxiety disorders, is noninferior to CBT, and provides an alternative strategy for treating anxiety in children. CLINICAL TRIAL REGISTRATION INFORMATION Explanatory Clinical Trial of a Novel Parent Intervention for Childhood Anxiety (SPACE); https://clinicaltrials.gov; NCT02310152.

中文翻译：

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以父母为基础的治疗与儿童焦虑症的认知行为疗法一样有效：支持性父母对于儿童期情绪的非劣效性研究。

目的在许多情况下，对儿童焦虑症的治疗不足。已经检查了父母的参与以增强基于儿童的认知行为疗法（CBT），但是尚无研究将独立的基于父母的疗法与CBT的疗效进行比较。研究表明家庭住宿对儿童焦虑症的维持和病程的影响。支持性父母对儿童期情绪的忧虑（SPACE）是一种基于父母的治疗方法，可以减少儿童期焦虑症的负担。这项研究在一项非劣效性试验中将SPACE与CBT进行了比较。方法参与者是患有原发性焦虑症的儿童（N = 124； 7-14岁； 53％的女性参与者； 83％的白人），被随机分配到没有直接与儿童治疗师接触的CACE（n = 64）或CBT中（n = 60），无父母治疗。共有97位参与者（78％）完成了所有治疗课程和评估。两组之间的损耗没有显着差异。主要的焦虑结局包括诊断性访谈和临床医师评定的量表。次要结局包括父母和孩子对焦虑严重程度，家庭住宿和育儿压力的评估。根据统计和临床考虑确定非劣效性边缘。使用混合模型分析研究了家庭住宿和父母压力的变化。结果在主要和次要焦虑结局方面，基于独立评估者，父母和孩子提供的评分，相对于CBT，SPACE成绩不逊于其他。两种治疗均显着降低了家庭住宿和育儿压力，与CBT相比，SPACE后家庭住所的减少显着更大。治疗的可信度和满意度很高。结论SPACE是治疗儿童焦虑症的一种可接受且有效的方法，不亚于CBT，并为儿童焦虑症的治疗提供了另一种策略。临床试验注册信息新型父母干预儿童期焦虑症（SPACE）的解释性临床试验；https://clinicaltrials.gov; NCT02310152。临床试验注册信息新型父母干预儿童期焦虑症（SPACE）的解释性临床试验；https://clinicaltrials.gov; NCT02310152。临床试验注册信息新型父母干预儿童期焦虑症（SPACE）的解释性临床试验；https://clinicaltrials.gov; NCT02310152。