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Emergence of Candida auris in Russia
Journal of Hospital Infection ( IF 3.9 ) Pub Date : 2019-03-06 , DOI: 10.1016/j.jhin.2019.02.021
N.E. Barantsevich , O.E. Orlova , E.V. Shlyakhto , E.M. Johnson , N. Woodford , C. Lass-Floerl , I.V. Churkina , S.D. Mitrokhin , A.S. Shkoda , E.P. Barantsevich

This paper reports the emergence of Candida auris infections in an intensive care unit at a hospital in Moscow. Forty-nine cases were diagnosed in 2016–2017, and the risk factors and antifungal susceptibilities are described. The 30-day all-cause mortality for 19 bloodstream infections in patients who did not receive appropriate antifungal therapy was 42.1%. Phylogenetic analysis of the internal transcribed spacer and D1–D2 regions and K143R substitution in the ERG11 gene indicated that the studied C. auris strains were of South Asian origin. This first reported series of C. auris infections in Russia demonstrates the rapid dissemination of this species, and the need for international surveillance and control measures.



中文翻译:

的出现念珠菌耳俄罗斯

本文报道了在莫斯科一家医院的重症监护室中出现假丝酵母感染的情况。2016-2017年诊断出49例病例,并描述了危险因素和抗真菌药性。在未接受适当抗真菌治疗的患者中,19种血液感染的30天全因死亡率为42.1%。所述内转录间隔区和D1-D2区域和K143R取代在的系统发育分析ERG11基因表明,所研究的C.耳菌株南亚来源的。在俄罗斯首次报道的系列金黄色葡萄球菌感染证明了该物种的迅速传播,以及需要国际监测和控制措施的需要。

更新日期:2019-07-18
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