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Trends in Risk of Limitations in Instrumental Activities of Daily Living Over Age in Older Persons With and Without Multiple Chronic Conditions.
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences ( IF 5.1 ) Pub Date : 2020-01-01 , DOI: 10.1093/gerona/glz049
Sigrid Mueller-Schotte 1, 2, 3 , Nicolaas P A Zuithoff 1 , Yvonne T Van der Schouw 1 , Marieke J Schuurmans 1, 2 , Nienke Bleijenberg 1, 2
Affiliation  

BACKGROUND To investigate trends over age by comorbidity status for the risk of limitations in individual activities of daily living for community-living older persons. METHODS A longitudinal population-based study was conducted in 9,319 community-living Dutch persons aged 60 years and older. Self-reported multiple chronic conditions (MCC) and nine instrumental activities of daily livings (IADLs) were assessed in 15 studies of the Dutch National Care for the Elderly Program (TOPICS-MDS). Risks of limitations in IADLs, odds ratios (per 5 years), and rate ratios (per 5 years) were calculated with mixed logistic and negative binomial regression models with age as the underlying timescale, stratified by number of MCC (no, 1-2, ≥ 3 MCC), and corrected for confounders. RESULTS At inclusion, the number of IADL limitations was highest for the "≥3 MCC" group (2.00 interquartile range [1.00-4.00]) and equal for "no MCC" or "1-2 MCC" (1.00 interquartile range [0.00-2.00]). Trends of individual IADLs depicted a higher risk in IADL limitation with increasing age over 2 years of follow-up, except for handling finances for the "no MCC" group. The longitudinal age effect on IADL limitations varied subject to MCC, being strongest for the "no MCC" group for most IADLs; grooming and telephone use were almost unaltered by age and MCC. CONCLUSION We observed a decline in IADL functioning with increasing age over 2 years of follow-up in persons with and without MCC. The impact of MCC on IADL decline varied per IADL activity.

中文翻译:

有和没有多重慢性病的老年人在日常生活中进行工具活动的局限性风险趋势。

背景技术通过合并症状态调查年龄增长趋势,以了解在社区生活的老年人的日常个人活动中存在局限性的风险。方法在9319名60岁及以上的社区居住的荷兰人中进行了一项基于人群的纵向研究。在荷兰国家老年护理计划(TOPICS-MDS)的15项研究中,对自我报告的多种慢性病(MCC)和9种日常活动(IADL)进行了评估。IADL限制风险,比值比(每5年)和费率比(每5年)使用年龄作为基础时间尺度的混合Logistic和负二项式回归模型进行计算,并按MCC数量进行分层(否,为1-2) ,≥3 MCC),并针对混杂因素进行了更正。结果包括在内,“ 00四分位间距[0.00-2.00])。单个IADL的趋势表明,随着2年以上随访年龄的增长,IADL限制的风险较高,除了为“无MCC”组处理财务外。纵向年龄对IADL限制的影响随MCC的不同而变化,对于大多数IADL而言,“无MCC”组的影响最为明显;修饰和电话使用几乎不受年龄和MCC的影响。结论我们观察到有和没有MCC的患者,随着2年以上随访年龄的增长,IADL功能会下降。MCC对IADL下降的影响因IADL活动而异。00四分位间距[0.00-2.00])。单个IADL的趋势表明,随着2年以上随访年龄的增长,IADL限制的风险较高,除了为“无MCC”组处理财务外。纵向年龄对IADL限制的影响随MCC的不同而变化,对于大多数IADL而言,“无MCC”组的影响最为明显;修饰和电话使用几乎不受年龄和MCC的影响。结论我们观察到有和没有MCC的患者,随着2年以上随访年龄的增长,IADL功能会下降。MCC对IADL下降的影响因IADL活动而异。纵向年龄对IADL限制的影响随MCC的不同而变化,对于大多数IADL而言,“无MCC”组的影响最为明显;修饰和电话使用几乎不受年龄和MCC的影响。结论我们观察到有和没有MCC的患者,随着2年以上随访年龄的增长,IADL功能会下降。MCC对IADL下降的影响因IADL活动而异。纵向年龄对IADL限制的影响随MCC的不同而变化,对于大多数IADL而言,“无MCC”组的影响最为明显;修饰和电话使用几乎不受年龄和MCC的影响。结论我们观察到有和没有MCC的患者,随着2年以上随访年龄的增长,IADL功能会下降。MCC对IADL下降的影响因IADL活动而异。
更新日期:2019-02-17
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