Amberlyst A-21 supported CuI was found to be highly efficient novel heterogeneous catalyst for the three-component reaction between ketones, amines and alkynes, commonly called KA²-coupling. This inexpensive, easy-to-prepare, simple and recyclable catalyst has been employed in solventless conditions in the KA² coupling reaction involving both primary and secondary amines, ketones and various alkynes. The secondary and tertiary propargylamine products were obtained in good to excellent results in moderate reaction times.

中文翻译：

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绿色，无溶剂，多相催化下的KA ²偶联反应

发现Amberlyst A-21负载的CuI是高效的新型多相催化剂，用于酮，胺和炔烃之间的三组分反应，通常称为KA ²偶联。这种廉价，易于制备，简单且可回收的催化剂已在涉及伯胺和仲胺，酮和各种炔烃的KA ²偶联反应的无溶剂条件下使用。在中等反应时间下，获得了炔丙基胺的仲和叔产物，结果良好或优异。